Subunit structure of a cortical granule lectin involved in the block to polyspermy in Xenopus laevis eggs

FEBS Letters

Chamow, Steven M.¹  Hedrick, Jerry L.¹ 

[1] Department of Biochemistry and Biophysics, University of California, Davis, CA 95616, USA

关键词: Fertilization;    Crosslinking;    Deglycosylation;    Glycoprotein;    Lectin;    Peptide mapping;   

DOI  :  10.1016/0014-5793(86)81011-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The cortical granule lectin of Xenopus laevis eggs is a large molecular mass glycoprotein involved in the post-fertilization block to polyspermy. We have investigated the subunit structure of this lectin and found that the native molecule contains 10–12 monomers, each of which has considerable charge and size heterogeneity due to glycosylated side chains. In addition, significant amino acid sequence homology is indicated by peptide mapping of subunits separated by isoelectric focusing.

【 授权许可】

Unknown