A U3 RNA pseudogene in mouse: sequence and organization in genomic DNA

FEBS Letters

Bachellerie, J.P.¹  Qu, L.H.¹  Bouche, G.¹  Ferrer, P.¹ 

[1] Centre de Recherche de Biochimie et de Génétique Cellulaires du CNRS, Université Paul Sabatier, 31062 Toulouse cedex, France

关键词: U3 RNA Pseudogene Retroposon genomic DNA (Rodent) Evolution;   

DOI  :  10.1016/0014-5793(86)80834-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A mouse U3 RNA pseudogene has been identified; it corresponds to a U3B full length coding sequence with a 3'-oligo(A) tail, precisely flanked at both ends by a pair of 15 bp direct repeats. These structural features suggest that it has arisen through an RNA-mediated mechanism involving an insertion at staggered nicks in the genome. Sequence data indicate that this mouse specimen has been generated by a different event as compared to the recently described rat pseudogenes. It represents the first reported case, for a pseudogene of this class, to be present at more than one copy per genome.

【 授权许可】

Unknown