Solid‐phase peptide synthesis of human(Nle‐27)‐oxyntomodulin

FEBS Letters

Audousset-Puech, M.P.¹  Bataille, D.¹  Martinez, J.¹  Castro, B.¹  Jarrousse, C.¹  Dufour, M.¹  Kervran, A.¹ 

[1]Centre CNRS-INSERM de Pharmacologie-Endocrinologie, CCIPE, Rue de la Cardonille, 34094 Montpellier, France

关键词: Gastric acid secretion Oxyntomodulin Solid-phase peptide synthesis;   

DOI  :  10.1016/0014-5793(86)80535-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Oxyntomodulin is a peptide isolated from porcine intestine which consists of the whole glucagon sequence extended at its C-terminal part by a basic octapeptide. The analogue (Nle-27)-oxyntomodulin of the human sequence has been synthesized by solid-phase peptide synthesis, purified by HPLC and identified. Its biological activities are the same as those of the natural hormone.

【 授权许可】

Unknown