Synthesis of seven different homologous phytochelatins in metal‐exposed Schizosaccharomyces pombe cells

FEBS Letters

Zenk, M.H.¹  Grill, E.¹  Winnacker, E.-L.² 

[1] Lehrstuhl für Pharmazeutische Biologie, Universität München, Karlstrasse 29, D-8000 München 2 Martinsried, FRG;Genzentrum der Universität München, D-8033 Martinsried, FRG

关键词: Phytochelatin Heavy metal-binding peptide Induction kinetics Glutathione;   

DOI  :  10.1016/0014-5793(86)80309-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The family of heavy metal-sequestering peptides with the formula (γ-Glu-Cys) _n Gly; n = 2–8), the phytochelatins (PCs), are not restricted to higher plants. In Schizosaccharomyces pombe the occurrence of two of these peptides has previously been reported. Reinvestigation of the peptide pattern of the heavy metal-exposed fission yeast led to the discovery of five additional peptides, a pattern which now corresponds qualitatively exactly to the one in higher plants. From the kinetics of induction we propose that PCs are synthesized by consumption of glutathione or its biosynthetic precursor.

【 授权许可】

Unknown