Complete tyrosine O‐sulfation of gastrin in adult and neonatal cat pancreas

FEBS Letters

Andersen, B.N.¹  Cantor, P.¹  Rehfeld, J.F.¹ 

[1] University Department of Clinical Chemistry, Rigshospitalet, DK-2100 Copenhagen, Denmark

关键词: Cholecystokinin Gastrin Ontogeny Tyrosine Sulfation;   

DOI  :  10.1016/0014-5793(86)80175-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have found gastrin in both the adult and neonatal cat pancreas. In contrast with the main production sites, antrum and duodenum, gastrin in the pancreas occurs in a single molecular form, tyrosine O-sulfated gastrin-17. Since tyrosine sulfation increases the pancreozymic effect of gastrin, the complete sulfation seems functionally expedient.

【 授权许可】

Unknown