Iduronic acid: constituent of sulphated dolichyl phosphate oligosaccharides in halobacteria

FEBS Letters

Sumper, Manfred¹  Wieland, Felix¹  Lechner, Johann¹ 

[1] Lehrstuhlfür Biochemie I, Universität Regensburg, Universitätsstr. 31, D-8400 Regensburg, FRG

关键词: Iduronic acid Dolichyl oligosaccharide Glycoprotein biosynthesis Halobacteria;   

DOI  :  10.1016/0014-5793(86)80134-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The occurrence of iduronic acid in the cell surface glycoprotein of halobacteria is described. This hexuronic acid is not only found in protein-linked oligosaccharides in halobacteria but does also exist in the corresponding dolichol-linked precursors. These findings were unexpected, as iduronic acid is a typical constituent of animal glycosaminoglycans, and its biosynthesis is so far known to occur by epimerization of a glucuronic acid residue within the completed carbohydrate chain linked to protein.

【 授权许可】

Unknown