Indole ring binds to 7‐methylguanine base by π‐π stacking interaction

FEBS Letters

Minamino, Naoko¹  Doi, Mitsunobu¹  Inoue, Masatoshi¹  Danshita, Masaya¹  Ishida, Toshimasa¹  Kamiichi, Katsuhisa¹ 

[1] Department of Physical Chemistry, Osaka College of Pharmacy, 2-10-65 Kawai, Matsubara-City, Osaka 580, Japan

关键词: 7-Methylguanosine 5'-monophosphate Tryptamine X-ray analysis Crystal structure π-π stacking interaction;   

DOI  :  10.1016/0014-5793(86)80129-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Strong π-π stacking interaction between the indole ring and 7-methylguanine base was shown by X-ray crystal analysis of the 7-methylguanosine 5'-monophosphate-tryptamine complex. This interaction appears to be strengthened by the attachment of ribose and phosphate groups to the base.

【 授权许可】

Unknown