Glucosamine is a normal component of liver glycogen

FEBS Letters

Kirkman, Brent R.¹  Whelan, William J.¹ 

[1] Department of Biochemistry, University of Miami School of Medicine, PO Box 016129, Miami, FL 33101, USA

关键词: Liver glycogen;    Kidney glycogen;    Galactosamine;    Glucosamine;    N-Methylglucosamine;   

DOI  :  10.1016/0014-5793(86)80041-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

There have been several reports of the incorporation of glucosamine into liver glycogen by an intraperitoneal injection of galactosamine, but it has not previously been considered that glucosamine is a normal component of liver glycogen. We now report that glucosamine occurs endogenously in rabbit- and pig-liver glycogens in the amount of about 1 nmol per 10 mg glycogen. Like the glucosamine incorporated by exogenous administration of galactosamine, the endogenous glucosamine takes the place of 1,4-linked α-glucose residues. It is found in both the outer and inner chains of the glycogen molecule.

【 授权许可】

Unknown