Lack of nucleotide cleavage on the binding of G‐actin‐ATP to plasma gelsolin

FEBS Letters

Harris, Harriet E.¹ 

[1] AFRC Institute of Animal Physiology, Babraham, Cambridge CB2 4AT, England

关键词: Actin;    Gelsolin;    ATP;    Actin polymerisation;   

DOI  :  10.1016/0014-5793(85)80432-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

G-Actin-ATP bound to plasma gelsolin to form a 2:1 complex. The complex contained approximately equivalent amounts of nucleotide and actin. More than 84% of this nucleotide was ATP. Half of the bound nucleotide was displaced by cold chase and the remainder did not exchange, implying that the two actins in the complex are not equivalent.

【 授权许可】

Unknown