On the physico‐chemical rationale of the genetic code

FEBS Letters

Villems, Richard¹  Rèmme, Jaanus¹ 

[1] Laboratory of Molecular Genetics, Institute of Chemical Physics and Biophysics, 14/16 Kingissepa Street, 202400 Tartu, Estonian SSR, USSR

关键词: Factor F430;    Sirohydrochlorin;    Tetrapyrrole;    δ-Aminolevulinic acid S-Adenosylmethionine Methanobacterium thermoautotrophicum;   

DOI  :  10.1016/0014-5793(85)81015-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We analysed two different and seemingly independent aspects of protein biosynthesis: the primary structure of codons and the reactivity of aminoacyl groups. This analysis revealed that more reactive aminoacyl groups correspond to less stable codon-anticodon complexes. The possible meaning of such a correlation is discussed in terms of the kinetic proofreading theory.

【 授权许可】

Unknown