Autoregulation of heat‐shock system in Drosophila Melanogaster

FEBS Letters

Titarenko, Helen¹  Evgen'ev, Michael B.¹  Zatsepina, Olga L.¹ 

[1] Institute of Molecular Biology, USSR Academy of Sciences, Vavilov str. 32, Moscow B-334, USSR

关键词: Heat-shock protein;    Puffing;    Drosophila ts mutation;   

DOI  :  10.1016/0014-5793(85)80388-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The cells of the cell-lethal mutant 1(1)ts403 are characterized by an extremely low level of synthesis of heat-shock proteins (hsp) after temperature elevation. The mutation affects not only the kinetics of hsp synthesis but also the electrophoretic pattern of hsp. Studies of puffing, RNA and protein synthesis in the mutant strongly suggest that hsp are involved in the regulation of their own synthesis at the level of puff induction, transcription and translation.

【 授权许可】

Unknown