Isolation and characterization of dipeptidyl peptidase IV from human meconium

FEBS Letters

Molinaro, Maria Francesca³  Petrilli, Pasquale¹  Picone, Delia²  Auricchio, Salvatore³  Caporale, Carlo³  Fontanella, Angiola³  Pucci, Piero² 

[1] Istituto di Industrie Agrarie dell' Universita' di Napoli Parco Gussone, 80055 Portici, NapoliItaly;Dipartimento di Chimica Organica e Biologica, Universita' di Napoli, via Mezzocannone 16, 80134 Napoli, Italy;Clinica Pediatrica, Universita' di Napoli Gruppo di Fisiologia e Patologia dell' Apparate Digerente, CNR, via Pansini 5, 80131 Napoli Italy

关键词: Dipeptidyl peptidase IV Brush border enzyme Meconium Casomorphin Procasomorphin Fast atom bombardment mass spectrometry;   

DOI  :  10.1016/0014-5793(85)80621-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Dipeptidyl aminopeptidase IV (DAP-IV) (EC 3.4.14.1) was purified from meconium particles sedimenting at 105000 × g. Its molecular properties and activity on synthetic and natural substrates (casomorphin and procasomorphin) were investigated.

【 授权许可】

Unknown