Tetrahydromethanopterin, a coenzyme involved in autotrophic acetyl coenzyme A synthesis from 2 CO2 in Methanobacterium

FEBS Letters

Länge, S.¹  Fuchs, G.¹ 

[1] Abteilung Angewandte Mikrobiologie, Universität Ulm, Oberer Eselsberg M 23, D-7900 Ulm, FRG

关键词: Methanobacterium;    Methanopterin;    Autotrophy;    Acetyl-CoA synthesis;    Archaebacteria;    Pteridin;   

DOI  :  10.1016/0014-5793(85)80281-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Methanobacterium thermoautotrophicum, a methane forming archaebacterium, grows autotrophically by synthesizing activated acetic acid from 2 CO₂. It is demonstrated in vitro that the methyl group of acetate is derived from methenyl tetrahydromethanopterin, which is known to be a one-carbon carrying coenzyme in CO₂ reduction to methane. The direct acetate precursors are suggested to be methyl tetrahydromethanopterin (“activated methanol”) and “activated carbon monoxide”.

【 授权许可】

Unknown