An unusual lectin from stinging nettle (Urtica dioica) rhizomes

FEBS Letters

De Ley, Marc¹  Broekaert, Willem F.²  Peumans, Willy J.² 

[1] Rega Institute, K.U Leuven, Minderbroederstraat, 10, B-3030 Leuven, Belgium;Laboratorium voor Plantenbiochemie, KU Leuven, Kardinaal Mercierlaan, 92, B-3030 LeuvenBelgium

关键词: Urtica dioica;    Lectin;    Interferon;    Lymphocyte;    UDA;    Urtica dioica agglutinin;    SDS-PAGE;    SDS-polyacrylamide gel electrophoresis;    Con A;    concanavalin A;    SEA;    staphylococcal enterotoxin A;   

DOI  :  10.1016/0014-5793(84)80989-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

An unusual lectin has been isolated from stinging nettle (Urtica dioica L.) rhizomes. It is a small (8.5 kDa) monomeric protein with high contents of glycine, cysteine and tryptophan. The U. dioica agglutinin (UDA) is not blood group-specific and is specifically inhibited by N-acetylglucosamine oligomers. As compared to other plant lectins, UDA has a very low specific agglutination activity. Nevertheless, it induces HulFN-γ in human lymphocytes at concentrations comparable to those of other inducers.

【 授权许可】

Unknown