Fibre diffraction of lithium DNA shows structural variability and deviation from a regular helical structure for the B‐form

FEBS Letters

Dutta, Santanu¹  Sasisekharan, V.¹  Parrack, Pradip K.¹ 

[1] Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012, India

关键词: Fiber diffraction;    Lithium B-DNA;    Non-ideal helix;    Structural variation;    r.h.;    relative humidity;   

DOI  :  10.1016/0014-5793(84)80922-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Recently, reports have appeared which show structural variations in B-DNA and indicate deviations from a uniform helical structure. We report for the first time that these indications are also present in the B-form fibre diffraction patterns for the lithium salt of natural DNA. We have used an improved method of controlling the salt concentration in the fibres. Our results are based on the appearance and disappearance of meridional reflections on different layer lines depending upon the salt.

【 授权许可】

Unknown