The L7/L12 proteins change their conformation upon interaction of EF‐G with ribosomes

FEBS Letters

Gongadze, G.M.¹  Gudkov, A.T.¹ 

[1] Institute of Protein Research, Academy of Sciences of the USSR, Pushchino, Moscow Region, USSR

关键词: L7/L12 ribosomal protein;    Elongation factor G;    Ribosome trypsinolysis;    Translation;   

DOI  :  10.1016/0014-5793(84)80906-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The different functional complexes of ribosomes with elongation factor F (EF-G) were studied by digestion experiments with trypsin. It was found that upon interaction of EF-G with ribosomes the L7/L12 proteins are sensitive to trypsin and are trypsin resistant after dissociation of EF-G from ribosomes. The significance of conformational alterations in the L7/L12 and also in the other proteins in the translation process is discussed.

【 授权许可】

Unknown