Activation of cGMP phosphodiesterase by purified green rod pigment from frog retina

FEBS Letters

Shinozawa, Takao²  Makino-Tasaka, Momoyo¹  Suzuki, Tatsuo¹ 

[1] Department of Pharmacology, Hyogo College of Medicine, Nishinomiya, Hyogo 663, Japan;Department of Biophysics, Faculty of Science, Kyoto University, Kyoto 606 Japan

关键词: Frog retina;    Green rod pigment;    Rhodopsin;    cGMP;    Phosphodiesterase;    Visual excitation;    PDE;    phosphodiesterase;    ROS;    rod outer segments;    GRP;    green rod pigment;    SDS-PAGE;    sodium dodecyl sulfate-polyacrylamide gel electrophoresis;   

DOI  :  10.1016/0014-5793(84)80575-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Activation of cGMP phosphodiesterase(PDE) of frog rod outer segments (ROS) by purified green rod pigment (GRP) was analyzed. GRP activated PDE in a similar manner to purified rhodopsin. This activation required illumination of the pigment and presence of GTP.

【 授权许可】

Unknown