Mass spectral identification of the blocked N‐terminal tryptic peptide of the ATPase inhibitor from beef heart mitochondria

FEBS Letters

Tsugita, A.²  Dianoux, A.C.³  Przybylski, M.¹ 

[1] Institut für Organische Chemie, Johannes Gutenberg, Universität Mainz, JJ Becker Weg 18-20, 6500 Mainz, FRG;European Molecular Biology Laboratory, Meyerhofstrasse L, Postfach 102 209, 6900 Heidelberg, FRG;Laboratoire de Biochimie (INSERM U.191 et CNRS/ERA 903), Département de Recherche Fondamentale, Centre d'Etudes Nucléaires, 85X, 38041 Grenoble Cédex, France

关键词: ATPase inhibitor;    N-formyi blocking group;    Fast atom bombardment;    Field desorption Amino acid sequence;   

DOI  :  10.1016/0014-5793(84)81095-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The presence of a formyl blocking group at the N-terminus of the ATPase inhibitor has been identified and the partial sequence of the N-terminal peptide has been determined by fast atom bombardment and field desorption coupled to mass spectrometry. Minor discrepancies in amino acid sequence of the inhibitor between the present and published data [(1981) Proc. Natl. Acad. Sci. USA 78, 7403-7407] are reported and its relationships with other inhbitors are briefly discussed.

【 授权许可】

Unknown