Induced changes in the affinity of 1,25‐dihydroxyvitamin D3 receptors in chick intestine

FEBS Letters

Bar, Arie¹  Hurwitz, Shmuel¹  Rosenberg, Jacob¹ 

[1] Institute of Animal Science, Agricultural Research Organization, The Volcani Center, P.O.B. 6, Bet Dagan 50250, Israel

关键词: Chick;    P-depletion;    Intestine;    1;    25-Dihydroxyvitamin D3;    Receptor;    Affinity;   

DOI  :  10.1016/0014-5793(83)80831-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The contents of 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) in plasma and intestinal mucose were increased by dietary calcium and by dietary phosphorus restriction. The concentration of intestinal occupied receptors for 1,25(OH)₂D₃ was higher in calcium-restricted birds. The affinity (association constant) of intestinal receptors for 1,25(OH)₂D₃ was lower in phosphorus-restricted chicks, as compared to control or calcium-restricted chicks. The number of binding sites were not influenced by dietary calcium or phosphorus restriction.

【 授权许可】

Unknown