The effects of mutations, deletions and insertions of single amino acids on the three‐dimensional structure of globins

FEBS Letters

Zharkikh, A.A.¹  Kolchanov, N.A.¹  Soloviov, V.V.¹ 

[1] Institute of Cytology and Genetics of the USSR Academy of Sciences, Siberian Department, Novosibirsk 630090, USSR

关键词: Mutation;    Deletion;    Insertion;    Protein structure;   

DOI  :  10.1016/0014-5793(83)80731-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Using the method of calculation of low energy packings of α-helices, we studied the effects of mutations, deletions and insertions of amino acids on the structure of sperm whale myoglobin. It was found that these events can cause complete breakdown of this structure.

【 授权许可】

Unknown