The relaxation time for a cruciform structure in superhelical DNA

FEBS Letters

Frank-Kamenetskii, M.D.¹  Vologodskii, A.V.¹ 

[1] Institute of Molecular Genetics, USSR Academy of Sciences, Moscow 123182, USSR

关键词: Cruciform structure;    Inverted repeat;    Palindrome;    Superhelical DNA;    Kinetics;    Relaxation time;    Superhelix density;   

DOI  :  10.1016/0014-5793(83)80960-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have calculated the relaxation time of a cruciform structure in superhelical DNA as a function of the superhelix density for palindromic regions of different lengths. The relaxation time has a sharp maximum at the superhelix density which corresponds to the equilibrium transition point between the cruciform structure and the regular double helix. This maximal value is shown to depend dramatically on the length of the palindromic region.

【 授权许可】

Unknown