The ratio between intrinsic 115 kDa and 30 kDa peptides as a marker of fibre type‐specific sarcoplasmic reticulum in mammalian muscles

FEBS Letters

Wiehrer, Walter¹  Pette, Dirk¹ 

[1] Fakultät für Biologie, Universität Konstanz, Postfach 5560, D-7750 Konstanz, FRG

关键词: Sarcoplasmic reticulum;    Muscle fibre type I;    IIA;    IIB;    Intrinsic membrane protein;    Chronic stimulation;   

DOI  :  10.1016/0014-5793(83)80604-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Sarcoplasmic reticulum displays characteristic differences in Ca²⁺-uptake, Ca²⁺-ATPase and the pattern of membrane proteins in type I, IIA and IIB fibres. The ratio between the 115 kDa Ca²⁺-ATPase and a 30 kDa protein is of characteristic magnitude in the sarcoplasmic reticulum of the three fibre types in rat muscles. The slow-to-fast fibre type transformation observed in rabbits during chronic nerve stimulation is accompanied by predictable changes of this ratio.

【 授权许可】

Unknown