Superoxide‐dependent formation of hydroxyl radicals in the presence of iron salts

FEBS Letters

Rowley, D.A.¹  Halliwell, B.¹  Flitter, W.¹ 

[1] Department of Biochemistry, King's College London, Strand, London, WC2R 2LS, England

关键词: Superoxide;    Hydroxyl radical;    Iron;    Haber—Weiss reaction;    Chelating agent;    Fenton reaction;   

DOI  :  10.1016/0014-5793(83)80602-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

In the presence of physiological concentrations of iron(III) salts, superoxide radical and hydrogen peroxide can interact to form the highly-damaging hydroxyl radical. No specific added ‘chelator’ of iron salts is necessary for this reaction to occur.

【 授权许可】

Unknown