An iron‐activated alcohol dehydrogenase

FEBS Letters

Scopes, R.K.¹ 

[1] Department of Biochemistry, La Trobe University, Bundoora, VIC 3083, Australia

关键词: Alcohol dehydrogenase Zymomonas mobilis Iron Ferrous Cobalt Product activation;   

DOI  :  10.1016/0014-5793(83)80517-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

An alcohol dehydrogenase isolated from Zymomonas mobilis was found to be activated by ferrous ions but not by zinc, after inactivation with metal-complexing agents. Cobaltous ions also re-activated to a lesser extent. It is suggested that in this species the alcohol dehydrogenase naturally contains iron. Kinetic studies on the iron-treated enzyme indicate an ‘alcohol activation’ phenomenon, which may have physiological relevance in overcoming product inhibition during fermentation.

【 授权许可】

Unknown