Characterisation of brain D2 dopamine receptors solubilised by lysophosphatidylcholine

FEBS Letters

Strange, Philip G.¹  Wheatley, Mark¹ 

[1] Department of Biochemistry, The Medical School, Queen's Medical Centre, Nottingham NG7 2UH, England

关键词: D2 dopamine receptor;    Solubilisation;    Lysophosphatidylcholine [3H]Spiperone Bovine caudate nucleus;    LPC;    lysophosphatidylcholine;   

DOI  :  10.1016/0014-5793(83)80351-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Brain D₂ dopamine receptors have been solubilised using lysophosphatidylcholine. The inclusion of proteinase inhibitors during solubilisation enables a preparation to be obtained containing a high proportion of solubilised D₂ receptors with pharmacological properties similar to those of membrane bound D₂ receptors.

【 授权许可】

Unknown