Poly(ADP‐ribose) synthetase inhibitors enhance streptozotocin‐induced killing of insulinoma cells by inhibiting the repair of DNA strand breaks

FEBS Letters

Yamamoto, Hiroshi¹  Okamoto, Hiroshi¹ 

[1] Department of Biochemistry, Toyama Medical and Pharmaceutical University, School of Medicine, Toyama 930-01, Toyama, Japan

关键词: Streptozotocin;    Insulinoma;    Poly(ADP-ribose) synthetase inhibitors;    Cancer treatment;    DNA strand breaks;    DNA repair;    RPMI 1640;    Roswell Park Memorial Institute Tissue Culture Medium 1640;    EGTA;    ethylene glycol bis(β-aminoethyl ether)N;    N-tetraacetic acid;   

DOI  :  10.1016/0014-5793(82)80187-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 授权许可】

Unknown