Dansylsphingolipids for labelling and probing membranes

FEBS Letters

Huang, Richard T.C.¹ 

[1] Institut für Virologie, Justus-Liebig-Universität Giessen, D-6300 Giessen, FRG

关键词: Dansylsphingolipid synthesis;    Membrane label;    Membrane probe;    Protein—lipid interaction;   

DOI  :  10.1016/0014-5793(82)81215-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Three fluorescent sphingolipids have been prepared, which contain dansyl sphingosine in the hydrophobic portion and various head groups (F-Phosphorylcholine, galactose and lactose) in the hydrophilic end. These dansylphingolipids are readily incorporated into membranes and show affinity toward several membrane proteins. Results of fluorescence measurements indicate, that these lipids may be useful as probes for studying protein—lipid interactions.

【 授权许可】

Unknown