Preparation of polyethylene glycol‐modified streptokinase with disappearance of binding ability towards anti‐serum and retention of activity

FEBS Letters

Koide, Atsushi¹  Suzuki, Suguru¹  Kobayashi, Seiichi¹ 

[1] Tsukuba Research Laboratory, Eisai Co. Ltd., 1-3, Tokodai 5-chome, Toyosato-machi, Tsukuba-gun, Ibaragi 300-26, Japan

关键词: Streptokinase;    Methoxypolyethylene glycol;    Antigenicity;    Enzymic activity;    Stability;    Chemical modification;   

DOI  :  10.1016/0014-5793(82)80276-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 授权许可】

Unknown