THE RELATIONSHIP BETWEEN CLINICOBIOCHEMICAL MARKERS AND DEPRESSION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

Iranian journal of reproductive medicine

HOSSEINI SEYED MOHAMMAD¹  MOADDAB AMIRHOSSEIN¹  ESNA ASHARI FARZANEH¹  RAHIMINEJAD MOHAMMAD EHSAN¹  RABIEE SOGHRA¹  BORZOUEI SHIVA¹ 

关键词: POLYCYSTIC OVARY SYNDROME;    DEPRESSION;    OBESITY;    HIRSUTISM;    COMPLICATION;   

DOI  :  

学科分类：药学、药理学、毒理学（综合）

来源: Shahid Sadoughi University of Medical Sciences, Yazd

【 摘 要 】

Background: Previous studies have demonstrated that clinical features of 16TPolycystic ovary syndrome16T (PCOS) are associated with a lower degree of health, self, and sex satisfaction.Objective: Our study aimed to investigate possible associations between depression and different clinicobiochemical markers of PCOS.Materials and Methods: In a cross-sectional analytic study, 120 PCOS women aged 18-45 yr, were enrolled. Beck Depression Inventory was used to assess depression. Also, all participants underwent biochemical studies. Individuals with 15 points and more in Beck test were referred to a psychiatrist to participate in a complementary interview for the diagnosis of depression based on Diagnostic and Statistical Manual of Mental Disorders IV (DSMIV-TR) criteria.Results: Among the study participants, 82 women (68.3%) were non-depressed, and 38 patients (31.7%) had some degrees of depression. According to the psychiatric interview, 10 patients (8.3%) had major depression, 22 patients (18.3%) had minor depression and 6 patients (5%) had dysthymia. We failed to show any significant difference in body mass index, hirsutism, infertility, serum total testosterone, lipid profile, and the homeostasis model assessment of insulin resistance (HOMA-IR) between depressed and non-depressed subjects (p>0.05). Using Spearman correlation, we did not find a positive correlation between BDI scores and clinicobiochemical markers for all PCOS subjects (-0.139?r?+0.121, p>0.05).Conclusion: In spite of high rate of depression in women with PCOS, there was no significant association between Clinicobiochemical Markers and depression.

【 授权许可】

Unknown