Iranian journal of reproductive medicine | |
THE RELATIONSHIP BETWEEN CLINICOBIOCHEMICAL MARKERS AND DEPRESSION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME | |
HOSSEINI SEYED MOHAMMAD1  MOADDAB AMIRHOSSEIN1  ESNA ASHARI FARZANEH1  RAHIMINEJAD MOHAMMAD EHSAN1  RABIEE SOGHRA1  BORZOUEI SHIVA1  | |
关键词: POLYCYSTIC OVARY SYNDROME; DEPRESSION; OBESITY; HIRSUTISM; COMPLICATION; | |
DOI : | |
学科分类:药学、药理学、毒理学(综合) | |
来源: Shahid Sadoughi University of Medical Sciences, Yazd | |
【 摘 要 】
Background: Previous studies have demonstrated that clinical features of 16TPolycystic ovary syndrome16T (PCOS) are associated with a lower degree of health, self, and sex satisfaction.Objective: Our study aimed to investigate possible associations between depression and different clinicobiochemical markers of PCOS.Materials and Methods: In a cross-sectional analytic study, 120 PCOS women aged 18-45 yr, were enrolled. Beck Depression Inventory was used to assess depression. Also, all participants underwent biochemical studies. Individuals with 15 points and more in Beck test were referred to a psychiatrist to participate in a complementary interview for the diagnosis of depression based on Diagnostic and Statistical Manual of Mental Disorders IV (DSMIV-TR) criteria.Results: Among the study participants, 82 women (68.3%) were non-depressed, and 38 patients (31.7%) had some degrees of depression. According to the psychiatric interview, 10 patients (8.3%) had major depression, 22 patients (18.3%) had minor depression and 6 patients (5%) had dysthymia. We failed to show any significant difference in body mass index, hirsutism, infertility, serum total testosterone, lipid profile, and the homeostasis model assessment of insulin resistance (HOMA-IR) between depressed and non-depressed subjects (p>0.05). Using Spearman correlation, we did not find a positive correlation between BDI scores and clinicobiochemical markers for all PCOS subjects (-0.139?r?+0.121, p>0.05).Conclusion: In spite of high rate of depression in women with PCOS, there was no significant association between Clinicobiochemical Markers and depression.
【 授权许可】
Unknown
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