THE EFFECTS OF GINGER ON SPERMATOGENESIS AND SPERM PARAMETERS OF RAT

Iranian journal of reproductive medicine

FATHI AZAD F.¹  OZANCI CH.C.¹  HAMADEH M.¹  NOURI MOHAMMAD¹  KHAKI ARASH¹  GHAFARI NOVIN M.¹  KHAKI A.A.¹ 

关键词: GINGER RHIZOME;    SPERM;    SPERMATOGENESIS;    RAT;    TESTIS;    TESTOSTERONE;   

DOI  :  

学科分类：药学、药理学、毒理学（综合）

来源: Shahid Sadoughi University of Medical Sciences, Yazd

【 摘 要 】

Background: Ginger rhizome (Zingiber officinale R., family: Zingiberaceae) is used medicinally and as a culinary spice. Objective: Medicinal use of ginger dates back to ancient China and India. Ginger and its constituents are stated to have antiemetic, antithrombotic, antihepatotoxic, anti-inflammatory, stimulant, cholagogue and antioxidant. It has been used since ancient time as medicinal and food origins it contain antioxidative and androgenic activities and have well effect in diseases treatment in more countries world-wide. As an antioxidant’s ginger has a useful effect on spermatogenesis and sperm parameters. Materials and Methods: Wistar male rat (n=30) were allocated into three groups, control (n=10) and test groups (n=20), that subdivided into groups of 2 that received ginger rhizome powder (50 and 100mg/kg/day) for 20 consequence day. Animals were kept in standard conditions. In twentieth day the testes tissue of Rats in whole groups were removed and sperm was collected from epididymis and prepared for analysis. Results: Serum total testosterones significantly increased in experimental group that has received 100 mg/kg/day Ginger (p<0.05) in comparison to control group. Besides, the percentage of sperm viability and motility in both test groups significantly increased (p<0.05) in comparison to control group, Whereas, LH, FSH hormones, sperm concentration, morphology and testes weights in both experimental and control group were similar. Conclusion: Results revealed that administration of 100 mg/kg/day of ginger significantly increased sperm percentage, viability, motility and serum total testosterones. This suggested that ginger may be promising in enhancing sperm healthy parameters.

【 授权许可】

Unknown