Tissue Doppler Imaging Values in Hypertrophic Cardiomyopathy Accordingto Left Ventricular Outflow Gradient

Journal of Cardiovascular and Thoracic Research

Azin Alizadehasl¹  Rezvaneh Salehi¹ 

[1] Cardiovascular ResearchCenter, Tabriz University ofMedical Sciences, Tabriz, Iran.$$

关键词: Hypertrophic Cardiomyopathy;    Tissue Doppler Imaging;    Left Ventricular Outflow Gradient;   

DOI  :  

学科分类：农业科学（综合）

来源: Tabriz University of Medical Sciences and Health Services

【 摘 要 】

Background: The aim of the present study was to investigate the effects of the left ventricular outflow gradient on tissuedoppler imaging (TDI) values in patients with hypertrophic cardiomyopathy (HCM).Methods: This prospective observational study was conducted in a tertiary referral heart hospital (Tabriz, Iran) fromMarch 2004 to March 2008. Fifty two patients (28 men and 24 women) with definite diagnoses of HCM were selected forthe study. 2D, M-mode echocardiography and TDI were performed for all patients. In TDI, the velocities of myocardiumwas measured at lateral and septal corner of the mitral valve annulus in peak early diastolic (Ea), peak late diastolic (Aa)and peak systolic (Sa). Then, the TDI velocities were compared in patients with left ventricle outflow gradient less and morethan 30 mmHg.Results: The mean age of the patients was 42.13 ± 12.22 years. All patients were in New York Heart Association functionalclass I or II. The mean EF was 55 ± 7%. It was found that TDI velocities are reduced in patients with HCM, compared tonormal vaues and Ea in septal corners of the mitral annulus was reduced more in patients with left ventricle outflowgradient > 30 mmHg (5.3±1.6 vs 7.1±1.2, P=0.01).Conclusion: TDI findings specially peak early diastolic (Ea) mitral annular velocity are good parameters in HCM patientsassessment.

【 授权许可】

Unknown