Hypomagnesemia and vitamin D deficiency complicating bisphosphonate induced hypocalcaemia

Malta medical journal

Josephine Bigeni¹  Antoine Vella¹ 

关键词: Hypocalcaemia;    bisphosphonate;    vitamin D deficiency;    hypomagnesemia;   

DOI  :  

学科分类：医学（综合）

来源: University of Malta * Medical School

【 摘 要 】

Zolendronic acid is a potent bisphosphonate that is used to treat patients with metastatic cancer by reducing bone pain and preventing skeletal complications of bone metastasis.We reported the case of a lady suffering from metastatic breast cancer who developed seizures secondary to severe hypocalcaemia after being treated with Zolendronic acid.Hypocalcaemia was unresponsive to treatment until vitamin D and magnesium deficiencies were corrected.This case highlights the importance of taking serum magnesium and vitamin D levels in patients presenting with resistant hypocalcaemia following bisphosphonate administration, especially in those with underlying bone malignancy.

【 授权许可】

Unknown