A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices

Developmental Biology

John Mc Caffrey¹  Deirdre Kelly¹  Peter Mac Mahon²  Sarah Mc Erlean¹  Danielle Byrne² 

[1] Department of Oncology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland$$;Department of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland$$

关键词: Giant Cell Tumor;    Radiological Features;    Denosumab;   

DOI  :  10.1016/j.radcr.2016.04.009

学科分类：医学（综合）

来源: University of Washington * Department of Radiology

【 摘 要 】

Giant cell tumor of bone (GCTB) is a rare condition with distinct radiological features that aid diagnosis. We present the case of an adult female patient, with locally invasive GCTB and review important radiological and management principles. Specific radiological features include locally aggressive, lytic radiolucent lesions, which can demonstrate cortical thinning and expansile remodeling of bone and typically involve the epiphysis and metaphysis. Management is primarily surgical, and denosumab has a role in the advanced setting.

【 授权许可】

Unknown