Drug injection-related fat necrosis of the breast with FDG PET-CT uptake

Developmental Biology

Diana L. Lam¹  Lauren Kay Toney²  Habib Rabhar¹ 

[1] Division of Breast Imaging, Department of Radiology, University of Washington School of Medicine, Seattle, WA, USA$$;Division of Nuclear Medicine, Department of Radiology, University of Washington School of Medicine, Box 357115, Seattle, WA, 98195-7115, USA$$

关键词: Breast;    Fat necrosis;    Intravenous drug use;    FDG PET-CT;    Breast lump;   

DOI  :  10.1016/j.radcr.2015.05.001

学科分类：医学（综合）

来源: University of Washington * Department of Radiology

【 摘 要 】

A 52-year-old woman was found to have a lung mass and bilateral breast lesions on computed tomography (CT). Subsequent positron emission tomography/CT demonstrated marked uptake in the lung mass and mild uptake within the breast lesions. A diagnostic mammogram and targeted ultrasound were performed to exclude primary breast malignancy or metastases from presumed pulmonary malignancy. A pertinent history of recent intravenous drug use with heroin injection into bilateral breasts, together with imaging features, facilitated diagnosis of fat necrosis. Fat necrosis is a common diagnosis in breast imaging and may be an incidental finding on positron emission tomography/CT in the oncologic setting. The presence of fat along with suggestive clinical history can lead to the diagnosis and appropriate assignment of either benign, breast imaging-reporting and data system (BI-RADS) 2, or probably benign, BI-RADS 3, category with short interval follow-up. Appropriate work-up of incidental fluorodeoxyglucose-avid breast masses with diagnostic mammogram ± ultrasound is warranted to avoid incorrect interpretation as neoplastic processes.

【 授权许可】

Unknown