Antimicrobial sensitivity patterns of cerebrospinal fluid (CSF) isolates in Namibia: implications for empirical antibiotic treatment of meningitis

Journal of Pharmaceutical Policy and Practice

Lazarus Indongo¹  Francis Kalemeera¹  Christopher Ntege¹  David Mabirizi¹  Johannes Gaeseb¹  Christophine Ndjavera¹  Assegid Mengistu¹  Gottfried Uaaka¹  Kennedy Kambyambya¹  Mohan P Joshi¹  Evans Sagwa¹ 

[1] 1Ministry of Health and Social Services, Windhoek, Namibia

关键词: Celebrospinal fluid;    Antimicrobial resistance;    Culture and sensitivity;    Empiric therapy;    Meningitis;    Namibia;   

DOI  :  10.1186/2052-3211-6-4

学科分类：药理学

来源: BioMed Central

【 摘 要 】

Objective

Bacterial meningitis is a medical emergency associated with high mortality rates. Cerebrospinal fluid (CSF) culture is the “gold standard” for diagnosis of meningitis and it is important to establish the susceptibility of the causative microorganism to rationalize treatment. The Namibia Standard Treatment Guidelines (STGs) recommends initiation of empirical antibiotic treatment in patients with signs and symptoms of meningitis after taking a CSF sample for culture and sensitivity. The objective of this study was to assess the antimicrobial sensitivity patterns of microorganisms isolated from CSF to antibiotics commonly used in the empirical treatment of suspected bacterial meningitis in Namibia.

【 授权许可】

Unknown