Image-guided percutaneous microwave ablation of small renal tumours: short- and mid-term outcomes

Quantitative Imaging in Medicine and Surgery

Lucy Di Marco¹  Eric Mourey²  Denis Krausé³  Sylvain Favelier³  Romaric Loffroy⁴  Morgan Moulin²  Olivier Chevallier³  Pierre-Yves Genson³  Jean-Pierre Cercueil³  Luc Cormier² 

[1] Department of Vascular, Oncologic and Interventional Radiology,Department of Radiology and Radiological Science, Medical University of South Carolina, MSC 323 Charleston, USA;Department of Urology and Andrology, François-Mitterrand Teaching Hospital, University of Dijon School of Medicine, 21079 Dijon Cedex, France;;Department of Vascular, Oncologic and Interventional Radiology,;Department of Vascular, Oncologic and Interventional Radiology, LE2I UMR CNRS 6306, Arts et Métiers, University of Bourgogne Franche-Comté, Dijon, France

关键词: Renal tumour;    thermal ablation;    microwave ablation (MWA);    nephrectomy;    outcomes;   

DOI  :  10.3978/j.issn.2223-4292.2015.10.02

学科分类：外科医学

来源: AME Publications

【 摘 要 】

Background: The purpose is to assess the short- and mid-term outcomes of microwave ablation (MWA) of small renal tumours in selected patients.

Methods: From August 2012 to February 2015, 29 renal tumours in 23 patients (17 male, 6 female, mean age 75 years) were treated by percutaneous MWA under imaging guidance. The tumours were 1-4.7 cm in diameter (mean size, 2.7 cm). Therapeutic effects were assessed at follow-up with magnetic resonance imaging (MRI). All patients were followed up for 2-25 months (mean, 12.2 months) to observe the therapeutic effects and complications. Changes in renal function at day 1 after treatment were statistically analyzed using the Student paired t-test or the paired Wilcoxon test.

Results: Technical success was achieved in all cases. One severe bleeding complication post-procedure occurred leading to death. No other unexpected side effects were observed after the MWA procedures. Clinical effectiveness was 100%. None of the patients showed recurrence on MRI imaging follow-up. No significant changes in renal function were noted after treatment (P=0.57).

Conclusions: Our preliminary study demonstrates that the use of MWA for the treatment of small renal tumours can be applied as safely and efficiently as other ablative techniques in selected patients not eligible for surgery.

【 授权许可】

Unknown