In vitro assessment of the antimicrobial activities of leaf and stem extracts of Alchornea cordifolia

Journal of Applied Sciences and Environmental Management

OWOSENI, ABIMBOLA A.¹  AMJO, OLUBUNMI D.¹  AYANSINA, AYANTADE D.¹ 

关键词: Alchornea cordifolia;    plant extracts;    antimicrobial;    bacteria;    fungi;   

DOI  :  

学科分类：环境科学（综合）

来源: University of Port Harcourt * Department of Pure and Industrial Chemistry

【 摘 要 】

In vitro assessment of the antimicrobial effect of leaf and stem extracts of acommonly used plant – Alchornea cordifoliawas carried out on 10 bacteria and 5 fungi. Fivesolvents– chloroform, methanol, ethanol, petroleum ether and water were used for extraction.Chloroform extract from leaf and stem resulted in the highest zone of inhibition against thetest bacteria (33 – 56mm). Ethanol extracts showed inhibition zone ranging between 10 –14mm; methanol extract showed inhibition zone of 13 – 21mm only for the leaf extract.Petroleum ether extract of only the stem resulted in inhibition of the test bacteria (10 –15mm). Leaf and stem water extracts did not result in any zone of inhibition. Only chloroformextracts from both leaf and stem resulted in fungal growth inhibition ranging from 22 – 60mm(leaf) and 14 – 40mm (stem). Staphylococcus haemolyticuswas most sensitive to leafchloroform extracts (50mm), followed by E. coli(49mm); while Salmonellasp. was the mostsensitive to stem extracts (56mm). Rhizopussp. was the most sensitive to both chloroformleaf extracts (60mm) and stem extracts (40mm) out of the 5 fungi screened. The highestminimum inhibition concentration (MIC) of 0.125mg/ml was obtained from the leafchloroform extract on Pseudomonassp. The implication of the findings was discussed.

【 授权许可】

Unknown