Journal of Applied Sciences and Environmental Management | |
Synthesis and Biological Activities of Some Benzimidazoles Derivatives | |
Al-Ebaisat, Hamdan S.1  | |
关键词: Benzimidazole; Antifungal Agent; Fungicides; Aldehyde; Derivative; Chemical Synthesis.; | |
DOI : | |
学科分类:环境科学(综合) | |
来源: University of Port Harcourt * Department of Pure and Industrial Chemistry | |
【 摘 要 】
A set of six novel benzimidazoles compounds were prepared, this includes 5-Nitro-2-phenyl -1-ethylbenzimidazol (5),2-(p-Bromophenyl)-5-nitro-1-ethylbenzimidazol (6), 2- (p-Bromophenyl- 5-nitro-1–cyclopentylbenzimidazol(7),2-(p-Bromophenyl)-5-nitro-1-cyclopentylbenzimidazol (8),5-Amino-2-(p-Bromophenyl)-1-ethylbenzimidazol (9), and 5-Amino-(2- (p- Bromophenyl)- 1- cyclopentylbenzimidazol (10). The chemical structures of thesecompounds were elucidated using NMR and elemental analysis. The biological activity of thesecompounds as fungicides was tested against three commercially known fungicides ( Candida albicans ,patient isolate Candida glabrataand Candida krusei ).The biological activity of two compounds was found to becomparable to that of the commercially available fungicides (6 and 9).
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010247818ZK.pdf | 83KB | download |