A Carbazole Based Bimodal “Turn-On” Fluorescent Probe for Biothiols (Cysteine/Homocysteine) and Fluoride: Sensing, Imaging and its Applications

Bulletin of the Korean chemical society

Dong Hoon Choi¹  Hak Joong Kim¹  Byungkwon Yoon¹  Jong Seung Kim¹  Rajesh Kumar¹  Min Ju Cho¹  Matinder Kaur¹ 

关键词: Carbazole probe;    Cysteine/homocysteine sensing;    Fluoride recognition;    Molecular keypad lock;    Bioimaging;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A well-known carbazole-based precursor (probe 1) was used for the detection of cysteine/homocysteine and fluoride. Probe 1 shows a “turn-on” response to cysteine/homocysteine and fluoride via enhancement in emission intensity at 442 nm and 462 nm respectively, in solutions and living cells. Furthermore, probe 1 behaves as a fluorescent molecular switch between cysteine/homocysteine and fluoride as the chemical inputs, which have been used for the development of a combinatorial logic circuit and a molecular keypad lock.

【 授权许可】

Unknown