Synthesis of Arene-Fused Isoindoline Derivatives from Morita-Baylis-Hillman Adducts by IMDA Reaction Using Z-Vinylarenes as 1,3-Dienes

Bulletin of the Korean chemical society

Ko Hoon Kim¹  Jae Nyoung Kim¹  Jin Woo Lim¹  Hye Ran Moon¹ 

关键词: Intramolecular Diels-Alder reaction;    Morita-Baylis-Hillman adducts;    Vinylarenes;    Isoindolines;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Intramolecular Diels-Alder (IMDA) reaction of vinylarenes bearing a Z-alkenyl tether, prepared from Morita- Baylis-Hillman (MBH) adducts, afforded arene-fused isoindoline derivatives in good yields. Vinylfurans, vinylthiophenes, and vinylnaphthalenes could be used successfully as dienes, while vinylbenzene failed under the same reaction conditions.

【 授权许可】

Unknown