Synthesis of 2-Substituted Benzofurans from o-Iodophenols and Terminal Alkynes with a Recyclable Palladium Catalyst Supported on Nano-sized Carbon Balls under Copper- and Ligand-Free Conditions

Bulletin of the Korean chemical society

Ok-Kyung Yang¹  Eul Kgun Yum¹  Ji-Eun Kim¹  Hee Jung Park¹ 

关键词: Benzofuran;    Nano-sized carbon balls;    Terminal alkynes;    Recyclable;    Palladium catalyst;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

We have developed a one-step synthesis of benzofurans from o-iodophenol and various terminal alkynes, by using Pd catalyst supported on nano-sized carbon balls (NCB) under copper- and ligand free conditions. This recyclable catalyst could be reused more than 5 times in the same heteroannulation reaction. The results have demonstrated that diverse 2-substituted benzofurans with tolerant functional groups can be prepared simply and conveniently under these conditions.

【 授权许可】

Unknown