Efficient Ring Opening Reaction of Epoxides with Oxygen Nucleophiles Catalyzed by Quaternary Onium Salt

Bulletin of the Korean chemical society

Choon Sup Ra¹  Dae Won Cho¹  Sung Hong Kim¹  Jin Won Kim¹  Gyoosoon Park¹ 

关键词: Ring opening reaction;    Epoxide;    Oxygen nucleophile;    Quaternary onium salt;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Ring opening reactions of epoxides with oxygen nucleophiles catalyzed by a variety of quaternary onium salt, such as ammonium or phosphonium salt were explored. The results showed that tetrabutylphosphonium bromide (TBPB) among salts serves as the most efficient catalyst for this process and that expoxide ring opening reactions with a variety of oxygen nucleophiles including carboxyic acid and phenol, promoted using this salt, lead to generate readily purifiable products in excellent yields.

【 授权许可】

Unknown