A Fast, Highly Efficient and Green Protocol for One-Pot Synthesis of 2,4,5-Trisubstituted Imidazoles Catalyzed by [TBA]2[W6O19] as a Reusable Heterogeneous Catalyst

Bulletin of the Korean chemical society

Abolghasem Davoodnia and Niloofar Tavakoli-Hoseini¹  Mozhgan Ashrafi¹ 

关键词: Heterogeneous catalysis;    Solvent-free conditions;    Tetrabutylammonium hexatungstate [TBA]2[W6O19];    2;    4;    5-Trisubstituted imidazoles;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A simple and efficient synthesis of 2,4,5-trisubstituted imidazoles was achieved via a one-pot three-component cyclocondensation of benzil, aromatic aldehydes, and ammonium acetate in the presence of a catalytic amount of tetrabutylammonium hexatungstate [TBA]2[W6O19] as a heterogeneous catalyst under thermal solvent-free conditions. The key features of this methodology are operational simplicity, high yields, short reaction times, and a recyclable catalyst with a very easy work up.

【 授权许可】

Unknown