Enantioselective Hydrosilylation of Imines Catalyzed by Diamine-Zinc Complexes

Bulletin of the Korean chemical society

Xinhui Feng¹  Jaesook Yun¹  Bu-Mahn Park¹ 

关键词: Amines;    Enantioselectiviy;    Hydrosilylation;    Imines;    Zinc;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

The efficient asymmetric hydrosilylation of imines in the presence of polymethylhydrosiloxane has been investigated by screening chiral diamine-zinc complexes. A series of chiral diamine ligands were prepared from optically pure 1,2-diphenyl-1,2-ethanediamine and screened for effectiveness. N-Benzylic substituents were required for high enantioselectivity; ligands with bulky groups or extra coordinating groups such as OH and S lowered the catalytic activity. The level of asymmetric induction was usually in >90% ee range for aromatic imine substrates. A linear correlation between the ee of the ligand and that of the product was observed, indicating the presence of a 1:1 ratio of ligand to metal coordination in the active catalytic complex.

【 授权许可】

Unknown