Synthesis of triazoloquinoxalines as Antitubercular Agents

Bulletin of the Korean chemical society

Dalip Kumar¹  Kondapalli Venkata Gowri Chandra Sekhar¹  Vajja Sambasiva Rao¹ 

关键词: Triazolo quinoxalines;    Antitubercular;    Iodobenzene diacetate;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

1,2,4-Triazoles and quinoxalines were found to display various pharmacological activities. Hence a series of 1- aryl-4-methyl-1,2,4-triazolo[4,3-a]quinoxalines were synthesized. Due to various advantages of organic reactions under solvent-free conditions these compounds were developed using iodobenzene diacetate under solvent-free conditions. The synthesized compounds were characterized by elemental microanalysis, infrared spectroscopy, 1H NMR, 13C NMR and HRMS. All the synthesized compounds were investigated for their antitubercular activity and 5g was found to the most active compound.

【 授权许可】

Unknown