Synthesis, Characterization, and Antibacterial Applications of Novel Copolymeric Silver Nanocomposite Hydrogels

Bulletin of the Korean chemical society

Hyeongrae Cha¹  K.S.V. krishna Rao¹  Yong Ill Lee¹  Daniel T. Thangadurai¹  V. Ramesh Babu¹  Woohong Joo¹  Yonghyun Kim¹  Changdae Kim¹ 

关键词: Acryloylphenylalanine;    Silver nanocomposite hydrogels;    Silver nanoparticles;    Swelling;    Antibacterial study;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Copolymeric silver nanocomposite hydrogels were synthesized by using acryloyl phenylalanine (APA), N`-isopropylacrylamide (NIPAM) and crosslinked by N,N-methylene bisacrylamide (MBA) via radical redox polymerization. Present study allows entrapping silver nanoparticles into hydrogel networks. UV-visible spectroscopy and X-ray diffraction (XRD) studies confirmed the formation of silver nanoparticles in hydrogel matrix. 11% of weight loss difference between hydrogel and silver nanocomposite hydrogel is clearly indicates the formation and silver nanoparticles by thermo-gravimetrical analysis. The order of swelling capacity values of hydrogels and silver nanocmposite hydrogels were found to be in the order of placebo copolymeric hydrogel >Ag-copolymeric silver nanocomposite hydrogels. The particle size of silver nanoparticles was analysed and are in the range of 5 - 10 nm which has been confirmed by transmission electron microscopy (TEM) as well as particle size analysis. The silver nanocomposite hydrogel has shown very good antibacterial activity on gram-positive and gram-negative bacteriocides.

【 授权许可】

Unknown