Asymmetric Michael Addition of Ketones to Nitroolefins Catalyzed by a New Chiral Catalyst

Bulletin of the Korean chemical society

Feng Feng Hu¹  Lian Jun Wang¹ 

关键词: Chiral catalyst;    Michael reaction;    Nitroolefin;    Ketone;    Enantioselectivity;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A new chiral catalyst was synthesized and found that it could catalyzed the asymmetric Michael reaction of ketones with nitroolefins smoothly at room temperature, giving the desired adducts in 71 - 92% yields with excellent diastereoselectivities and high enantioselectivities (up to 95% ee).

【 授权许可】

Unknown