期刊论文详细信息
Bulletin of the Korean chemical society | |
Rhodium-Catalyzed Reductive Decyanation of Nitriles Using Hydrosilane as a Reducing Agent: Scope, Mechanism and Synthetic Application | |
Ryo Nakamura1  Yusuke Kita1  Mamoru Tobisu1  Naoto Chatani1  | |
关键词: Reductive decyanation; Carbon-carbon bond activation; Rhodium catalyst; Hydrosilane; | |
DOI : | |
学科分类:化学(综合) | |
来源: Korean Chemical Society | |
【 摘 要 】
A rhodium-catalyzed reductive cleavage reaction of carbon-cyano bonds is developed using hydrosilane as a mild reducing agent. A wide range of nitriles, including aryl, benzyl, and �?-hydrogen containing alkyl cyanides are applicable to this decyanation reaction. The method is also applicable to organic synthesis, in which benzyl cyanide is used as a benzyl anion equivalent and a cyano group functions as a removable ortho-directing group.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010242110ZK.pdf | 404KB | download |