期刊论文详细信息
Bulletin of the Korean chemical society | |
Total Synthesis of (¡¾)-Aspidospermidine Starting from 3-Ethyl-5-bromo-2-pyrone | |
Hyun Kyu Cho1  Cheon Gyu Cho1  Nguyen Thanh Tam1  | |
关键词: Total synthesis; Aspidospermidine; Diels-Alder reaction; 3; 5-Dibromo-2-pyrone; Tandem reaction; | |
DOI : | |
学科分类:化学(综合) | |
来源: Korean Chemical Society | |
【 摘 要 】
A new synthetic route to (�?)-aspidospermidine was devised, starting from the cycloadduct of 3-ethyl-5-bromo-2- pyrone with vinyl sulfide through a tandem conjugate addition-alkylation sequence. The requisite 3-ethyl-5-bromo-2- pyrone was prepared via the C3-selective Pd-catalyzed coupling reaction with Et3Al-dimethylaminoethanol complex.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010241949ZK.pdf | 213KB | download |