1,3-Dichloro-5,5-dimethylhydantoin as a Novel and Efficient Homogeneous Catalyst in Biginelli Reaction

Bulletin of the Korean chemical society

Mahnaz Haghdoust¹  Fatemeh Shafiezadeh¹  Mostafa Gholizadeh¹  Seyedeh Fatemeh Hojati¹ 

关键词: 3;    4-Dihydropyrimidin-2(1H)-one;    1;    3-Dichloro-5;    5-dimethylhydantoin;    Homogeneous;    Aldehyde;    ¥â-Dicarbonyl;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A new and efficient method for the preparation of substituted 3,4-dihydropyrimidin-2(1H)-ones via Biginelli synthesis using catalytic amounts of 1,3-dichloro-5,5-dimethylhydantoin is presented. Short reaction times, easy work-up, high yields of products and stability, easy-handling, non-toxicity and cheapness of the catalyst are noteworthy advantages of the present work.

【 授权许可】

Unknown